Assistant Professor & Associate Head of the Department
Basic Sciences
IIT Guwahati
6
Chemoproteomics, Infectious Diseases, Tuberculosis, Nucleosides
Organic and Medicinal Chemistry, Infectious diseases, Synthetic Lipids, Chemosproteomics
PhD in Chemistry from IIT Guwahati
M.Sc in Chemistry from IIT Guwahati
B.Sc in Chemistry (Hons) from Midnapore College
Assistant Professor at SR University, Warangal, from 2025-08-05 to .
Postdoctoral Associate at University of Minnesota, USA, from 2020-03-09 to 2025-03-08.
Research Scientist at TCG Lifesciences, Kolkata, from 2019-05-20 to 2020-01-31.
Researcher at UNIST, South Korea, from 2018-12-01 to 2019-03-08.
Ph.D
1. Qiang Liu, Q.; Ge, P.; Engelhart, C.A.; McCue, B.; Zimmerman, M.; Manna, A.C.; Panda, S.; Bockman, M. R.; Hegde, P. V.; Wallach, B. J.; Wong, T. K.; Cheung, A.; Finzel, B.C.; Dartois, V.; Schnappinger, D.;* Aldrich, C.C.* “Investigation of Bio-AMS ((5?-[N-(d-biotinoyl)sulfamoyl]amino-5?-deoxyadenosine)): A Potent Nucleoside-Based Antimicrobial Agent Inhibits Biotin Protein Ligase.” J. Med. Chem. 2025, 68 (3) 3065–3087. 2. Panda, S.; Orimoloye, O. M.; Poudel, T. N.; Jonghe, S.D.; Jochmans, D.; Neyts, J.; Aldrich, C. C.* “Protecting Group Control of Hydroxyketone-Hemiketal Tautomeric Equilibrium Enables Stereoselective Synthesis of a 1'-Azido C-Nucleoside.” J. Org. Chem. 2024, 89, 23, 17389–17399. 3. Sharma, S.; Hegde, P.; Panda, S.; Orimoloye, O. M.; Aldrich, C. C.* “Drugging the microbiome: targeting small microbiome molecules.” Curr. Opin. Microbiol., 2023, 71, 102234. 4. Poudel, T. N.+; Panda, S.+; Orimoloye, O. M.+; Hegde, P.; Aldrich, C. C.* “1?-Cyano Intermediate Enables Rapid and Stereoretentive Access to 1?-Modified Remdesivir Nucleosides.” J. Org. Chem., 2022, 87 (21), 14452-14462. (+ = Equal Contribution). 5. Panda, S.; Poudel, T. N.; Hegde, P.; Aldrich, C. C.* “Innovative Strategies for the Construction of Diverse 1?-Modified C-Nucleoside Derivatives.” J. Org. Chem., 2021, 86 (23), 16625-16640. 6. Panda, S.; Prdhan, N.; Chatterjee, S.; Morla, S.; Saha, A.; Roy, A.; Kumar, S.; Bhattacharyya, A.; Manna, D. * “4,5-Disubstituted 1,2,3-triazole Scaffold-Based Potent Inhibitors of Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase 1.” Sci. Rep.,2019, 9, 18455. 7. Panda, S.; Pradhan, N.; Manna, D.* “Ring-opening of Indoles: An unconventional route for the transformation of indoles to 1H-pyrazoles using Lewis Acid” ACS Comb. Sci., 2018, 20 (10), 573–578. 8. Saha, A.+; Panda, S.+; Pradhan, N.; Kalita, K.; Vishal, T.; Manna. D.* “Azidophosphonate chemistry as route for a novel class of vesicle forming phosphonolipids” Chem. Eur.J.2018, 24, 1121 –1127. (+ = Equal Contribution). 9. Akhtar, N.; Saha, A.; Kumar, V.; Pradhan, N.; Panda, S.; Morla, S.; Kumar, S.; Manna, D.* “Diphenylethylenediamine-Based Potent Anionophores: Transmembrane Chloride Ion Transport and Apoptosis Inducing Activities” ACS Appl. Mater. Interfaces, 2018, 10 (40), 33803–33813. 10. Panda, S.; Maity, P.*; Manna, D.* “Transition metal, azide and oxidant free homo- and heterocoupling of ambiphilic tosylhydrazones to the regioselective triazoles and pyrazoles” Org. Lett. 2017, 19(7), 1534-1537. 11. Paul, S.; Roy, A.; Deka, S. J.; Panda, S.; Srivastava, G. N.; Trivedi, V.; Manna, D. * “Synthesis and evaluation of oxindoles as promising inhibitors of the immunosuppressive enzyme indoleamine 2, 3-dioxygenase 1” Med Chem Comm. 2017, 8 (8), 1640-1654. 12. Panda, S.+; Roy, A.+; Deka, S. J.; Trivedi, V.; Manna, D.* “Fused heterocyclic compounds as potent indoleamine-2,3-dioxygenase 1 inhibitors” ACS Med. Chem. Lett. 2016, 7(12), 11671172. (+ = Equal Contribution). 13. Saha, A.+; Panda, S.+; Paul, S.+; Manna. D* “Phosphate bioisostere containing amphiphiles: a novel class of squaramide-based lipids” Chem. Commun., 2016, 52, 9438-9441. (+ = Equal Contribution). 14. Paul, S.; Roy, A.; Deka, S. J.; Panda, S.; Trivedi, V.*; Manna, D.* “Nitrobenzofurazan derivatives of N'-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1” Eur. J. Med. Chem. 2016, 121, 364-375. 15. Borah, R.; Mamidi, N.; Panda, S.; Gorai, S.; Pathak, K., S.; Manna, D.* “Elucidating the Interaction of ?-Hydroxymethyl-?-butyrolactone Substituents with Model Membranes and Protein Kinase C-C1 Domains” Mol. BioSyst. 2015, 11 (5), 1389-1399. 16. Mamidi, N.+; Panda, S.+; Borah, R.; Manna, D.* “Synthesis and Protein Kinase C (PKC)-C1 Domain Binding Properties of Diacyltetrol Based Anionic Lipids” Mol. BioSyst. 2014, 10 (11), 3002-3013. (+ = Equal Contribution). 17. Talukdar, D.+; Panda, S.+; Borah, R.+; Manna, D.* “Membrane Interaction and Protein Kinase C-C1 Domain Binding Properties of 4-hydroxy-3-(hydroxymethyl) Phenyl ester Analogues” J. Phys. Chem. B. 2014, 118 (27), 7541-7553.(+ = Equal Contribution). 18. Paul, S.; Panda, S.; Manna, D.* “Mild method for the synthesis of 1H-indazoles through oximephosphonium ion intermediate” Tetrahedron Lett. 2014, 55, 2480-2483.
Next generation remdesivir antivirals”, US Patent App. 17/579,271, 2022. Inventors: Courtney C Aldrich, Subhankar Panda, Tej Poudel
Triazole Derivatives and a Method of Its Preparation”, Application No. 201731045989; TEMP/E-1/46735/2017-KOL. Inventors: Debasis Manna, Subhankar Panda, Nirmalya Pradhan, Ashalata Roy, Sachin Kumar
