faculty-profile

Dr. Ayan Kumar Barui

info

Associate Professor

Department of Chemistry

Ph.D

11 Years

web-pages

Chemical Biology, Nanobiotechnology, Biomaterials, Nanotoxicology

Nanomedicine, Angiogenesis, Drug Delivery, Bioimaging, Vascular Diseases, Ischemic Diseases, Cancer Nanotechnology

Educational
Qualifications
(From Highest)

2017

Ph.D in Nanomedicine from CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India

2011

M.Sc in Chemistry from the University of Burdwan, West Bengal, India

2009

B.Sc in Chemistry (Hons.) from the University of Burdwan, West Bengal, India

Professional
Experience

2024

Associate Professor at SR University, Warangal, India, from 2024-11-11 to .

2022

Specialist at University of California Irvine (UCI), California, USA, from 2022-11-22 to 2024-10-31.

2021

Postdoctoral Fellow at Chapman University, California, USA, from 2021-11-12 to 2024-10-31.

2020

Associate Principal Scientist at Patanjali Research Foundation, Haridwar, India, from 2020-08-07 to 2020-12-08.

2018

Postdoctoral Research Associate at Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea, from 2018-01-01 to 2020-03-07.

Key Publications

Alanazi, A.; Barui, A. K.; Mohieldin, A. M.; Gupta, A.; Ramchandran, R.; Nauli, S. M.* Identifying the roles of miR-17 in ciliogenesis and cell cycle. Frontiers in Cell and Developmental Biology 2024, 12, 1-18. ISI 2023 IF # 4.6.

Goel, V.$; Barui, A. K.$ (Co-First Author); Nauli, S. M.* “Measuring calcium signaling at the primary cilia”; Book title: “Calcium Signaling”; Series title: “Methods in Molecular Biology”; Editor: Caroline M. Gorvin; Publisher: Springer Nature; 2024; ISBN: 978-1-0716-4163-7. [$First two authors have equal contribution]

Oh J. Y.$; Seu, M-S.$; Barui, A. K.$ (Co-First Author); Ok, H. W.; Kim, D.; Choi, E.; Seong, J.; Lah, M. S.; Ryu, J-H.* A multifunctional protein pre-coated metal-organic framework for targeted delivery with deep tissue penetration. Nanoscale 2024, 16, 14748-14756. ISI 2023 IF # 5.8. [$First three authors have equal contribution]

Pala, R.*; Barui, A. K.; Mohieldin, A. M.; Zhou, J.; Nauli, S. M.* Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses. Biomaterials 2023, 302, 122329. ISI 2023 IF # 12.8.

Barui, A. K.; Bollu, V. S. Londhe, S.; Deshpande, S. S.; Das, S.; Nethi, S. K.; Alabbasi, M. M. A.; Kuncha, M.; Kumar, J. M.; Sistla, R.; Misra, S.; Patra, C. R.* Toxicological evaluation of therapeutically active zinc oxide nanoflowers in pre-clinical mouse model. NanoImpact 2023, 31, 100479. ISI 2023 IF # 4.7.

Alshammari, Q. A.; Pala, R.; Barui, A. K.; Alshammari, S.; Nauli, A. M.; Katzir, N.; Mohieldin, A. M.; Nauli, S. M.* The use of advanced spectral imaging to reveal nanoparticle identity in biological samples. Nanoscale 2022, 14, 4065-4072. ISI 2023 IF # 5.8. [Featured in the front cover page of the journal “Nanoscale”]

Nethi, S. K.$; Barui, A. K.$ (Co-First Author); Jhelum, P.; Basuthakur, P.; Bollu, V. S.; Reddy, B. R.; Chakravarty, S.*; Patra, C. R.* Europium hydroxide nanorods mitigate hind limb ischemia in Wistar rats. Advanced Therapeutics 2021, 4, 2100016. ISI 2023 IF # 3.7. [$First two authors have equal contribution]

Mishra, A.*; Singla, S.; Barui, A. K.* “Green synthesis of inorganic nanoparticles and their cancer theranostics applications”; Book title: “Biogenic Nanoparticles for Cancer Theranostics”; Editor: Dr. Chittaranjan Patra et al.; Elsevier, 2021; ISBN: 978-012-82-1467-1. [*Corresponding author]

Barui, A. K.*; Nethi, S. K.; Basuthakur, P.; Jhelum, P.; Bollu, V. S.; Reddy, B. R.; Chakravarty, S.*; Patra, C. R.* Therapeutic angiogenesis using zinc oxide nanoflowers for the treatment of hind limb ischemia in rat model. Biomedical Materials 2021, 16, 044103. ISI 2023 IF # 3.9. [*Corresponding author]

Barui, A. K.; Roy, A.; Das, S.; Bhamidipati, K.; Patra, C. R.* “Therapeutic applications of graphene oxides in angiogenesis and cancers”; Book title: “Nanoparticles and Their Biomedical Applications”; Editor: Dr. Ashutosh K. Shukla; Springer Nature, 2020; ISBN: 978-981-15-0391-7. 

Jeena, M. T.; Lee, S.; Barui, A. K.; Jin, S.; Cho, Y.; Hwang, S-W.; Kim. S.*; Ryu, J-H.* Intra-mitochondrial self-assembly to overcome the intracellular enzymatic degradation of l-peptides. Chemical Communications 2020, 56, 6265-6268. ISI 2023 IF # 4.3.

Das, S.; Roy, A.; Barui, A. K.; Alabbasi, M. M. A.; Kuncha, M.; Sistla, R.; Sreedhar, B.; Patra, C. R.* Anti-angiogenic vanadium pentoxide nanoparticles for the treatment of melanoma and their in vivo toxicity study. Nanoscale 2020, 12, 7604-7621. ISI 2023 IF # 5.8.

Barui, A. K.; Oh, J. Y.; Jana, B.; Kim, C.*; Ryu, J-H.* “Cancer-targeted nanomedicine: overcoming the barrier of protein corona”. Advanced Therapeutics 2020, 3, 1900124. ISI 2023 IF # 3.7.

Barui, A. K.; Jhelum, P.; Nethi, S. K.; Das, T.; Bhattacharya, D.; Vinothkumar, B.; Karri, S.; Chakravarty, S.*; Patra, C. R.* Potential therapeutic application of zinc oxide nanoflowers in cerebral ischemia rat model through neuritogenic and neuroprotective properties. Bioconjugate Chemistry 2020, 31, 895-906. ISI 2023 IF # 4.

Barui, A. K.; Jana, B.; Ryu, J. H.* “An insight into characterizations and applications of nanoparticulate targeted drug delivery systems”; Book title: “Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy”; Editor: Dr. SSR Kumar Challa; Publisher: Springer Nature, 2019; ISBN: 978-3-662-59596-1.

Barui, A. K.; Das, S.; Patra, C. R.* “Biomedical applications of green synthesized metal nanoparticles using Polysaccharides”; Book title: “Functional Polysaccharides for Biomedical Applications”; Editor: Prof. Sougata Jana and Prof. Sabyasachi Maiti; Publisher: Elsevier Inc., 2019; DOI: 10.1016/B978-0-08-102555-0.00010-8; ISBN: 978-0-08-102555-0.

Bollu, V. S.$; Bathini, T.$; Barui, A. K.$ (Co-First Author); Roy, A.; Ragi N. C.; Maloth, S.; Sripadi, P.; Sreedhar, B.*; Nagababu, P.*; Patra, C. R.* Design of DNA-intercalators based copper(II) complexes, investigation of their potential anti-cancer activity and sub-chronic toxicity. Materials Science and Engineering C 2019, 105, 110079. ISI 2023 IF # 8.1. [$First three authors have equal contribution]

Nethi, S. K.$; Barui, A. K.$ (Co-First Author); Mukherjee, S.$; Patra, C. R.* “Engineered nanoparticles for effective redox signaling during angiogenic and anti-angiogenic therapy”. Antioxidants & Redox Signaling 2019, 30, 786-809. ISI 2023 IF # 5.9. [$First three authors have equal contribution]

Barui, A. K.; Nethi, S. K.; Haque, S.; Basu Thakur, P.; Patra, C. R.* “Recent development of metal nanoparticles for angiogenesis study and their therapeutic applications”. ACS Applied Bio Materials 2019, 2, 5492-5511. ISI 2023 IF # 4.6.

Barui, A. K.; Kotcherlakota, R.; Patra, C. R.* “Biomedical applications of zinc oxide nanoparticles”; Book title: “Inorganic Frameworks as Smart Nanomedicines”; Editor: Dr. Alexandru Mihai Grumezescu; Publisher: Elsevier-William Andrew, Copyright holder: Elsevier Inc., Oxford, UK and Cambridge, USA; 2018; DOI: 10.1016/B978-0-12-813661-4.00006-7; ISBN: 978-0-12-813661-4.

Barui, A. K.; Kotcherlakota, R.; Patra, C. R.* “Medicinal applications of metal nanoparticles”; Book title: “Metal Nanoparticles: Synthesis and Applications in Pharmaceutical Sciences”; Editor: Prof. Sreekanth Thota and Prof. Debbie C. Crans; Publisher: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany; 2018; DOI: 10.1002/9783527807093.ch5; ISBN: 978-3-527-33979-2.

Nethi, S. K.; Barui, A. K.; Bollu, V. S.; B. R. Rao; Patra, C. R.* Pro-angiogenic properties of terbium hydroxide nanorods: Molecular mechanisms and therapeutic applications in wound healing. ACS Biomaterials Science & Engineering 2017, 3(12), 3635-3645. ISI 2023 IF # 5.4.

Barui, A. K.; Kotcherlakota, R.; Bollu, V. S.; Nethi, S. K.; Patra, C. R.* “Biomedical and drug delivery applications of functionalized inorganic nanomaterials”; Book title: “Biopolymer-Based Composites: Drug Delivery and Biomedical Applications”; Editor: Prof. Sougata Jana, Prof. Sabyasachi Maiti and Prof. Subrata Jana; Publisher: Woodhead Publishing; Copyright holder: Elsevier Ltd., Duxford, UK, Cambridge, USA and Kidlington, UK; 2017; DOI: 10.1016/B978-0-08-101914-6.00011-9; ISBN: 978-0-08-101914-6 (print); ISBN: 978-0-08-101915-3 (online).

Barui, A. K.; Das, S.; Soanpet, P.; Sreedhar, B.; Patra, C. R.* Effective delivery of doxorubicin using biologically synthesized gold nanoparticles for cancer therapy. Journal of the Indian Chemical Society 2017, 94, 1335-1348. ISI 2023 IF # 3.2.

Barui, A. K.; Nethi, S. K.; Patra, C. R.* Investigation of the role of nitric oxide driven angiogenesis by zinc oxide nanoflowers. Journal of Materials Chemistry B 2017, 5, 3391-3403. ISI 2023 IF # 6.1.

Bollu, V. S.; Barui, A. K.; Mondal, S. K.; Prashar, S.; Fajardo, M.; Briones, D.; Rodríguez-Diéguez, A.; Patra, C. R.*; Gómez-Ruiz, S.* Curcumin-loaded silica-based mesoporous materials: Synthesis, characterization and cytotoxic properties against cancer cells. Materials Science and Engineering C 2016, 63, 393-410. ISI 2023 IF # 8.1.

Kotcherlakota, R.; Barui, A. K.; Prashar, S.; Fajardo, M.; Briones, D.; Rodríguez-Diéguez, A.; Patra, C. R.*; Gómez-Ruiz, S.* Curcumin-loaded mesoporous silica: An effective drug delivery system for cancer treatment. Biomaterials Science 2016, 4, 448-459. ISI 2023 IF # 5.8.

Kulhari, H.; Pooja, D.; Shrivastava, S.; Reddy, T. S.; Barui, A. K.; Patra, C. R.; Naidu, V. G. M.; Adams, D. J.; Sistla, R.* “Cyclic-RGDfK-directed docetaxel loaded nanomicelles for angiogenic tumor targeting” in “Springer Protocols”; Series title: “Methods in Pharmacology and Toxicology”; Publisher: Humana Press; Copyright holder: Springer Science + Business Media, New York; 2015; DOI: 10.1007/7653_2015_63; ISBN: 978-1-4939-7445-0 (online).

Wei, P-F.; Jin, P-P.; Barui, A. K.; Hu, Y.; Zhang, L.; Zhang, J-Q.; Shi, S-S.; Zhang, H-R.; Lin, J.; Zhou, W.; Zhang, Y-J.; Ruan, R-Q.; Patra, C. R.*; Wen, L-P.* Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment. Biomaterials 2015, 73, 160-174. ISI 2023 IF # 12.8.

Shaikh, A. C.; Shalini, S.; Vaidhyanathan, R.; Mane, M. V.; Barui, A. K.; Patra, C. R.; Venkatesh, Y.; Bangal, P. R.; Patil, N. T.* Identifying solid luminogens through gold-catalysed intramolecular hydroarylation of alkynes. European Journal of Organic Chemistry 2015, 2015, 4860-4867. ISI 2023 IF # 2.5.

Mukherjee, S.; Sreeram, P.; Barui, A. K.; Nethi, S. K.; Veeriah, V.; Chatterjee, S.; Suresh, K. I.; Patra, C. R.* Graphene oxides show angiogenic properties. Advanced Healthcare Materials 2015, 4(11), 1722-1732. ISI 2023 IF # 10. [Highlighted in “Nature India” and “Chemistry Views”]

Patra, S.; Mukherjee, S.; Barui, A. K.; Ganguly, A.; Sreedhar, B.; Patra. C. R.* Green synthesis, characterization of gold and silver nanoparticles and their potential application for cancer therapeutics. Materials Science and Engineering C 2015, 53, 298-309. ISI 2023 IF # 8.1.

Kulhari, H.; Pooja, D.; Shrivastava, S.; Telukutala, S. R.; Barui, A. K.; Patra, C. R.; Vegi, G. M. N.; Adams, D. J.; Sistla, R.* Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours. Nanomedicine: Nanotechnology, Biology, and Medicine 2015, 11, 1511-1520. ISI 2023 IF # 4.2.

Nethi, S. K.; Veeriah, V.; Barui, A. K.; Rajendran, S.; Mattapally, S.; Misra, S.; Chatterjee, S.*; Patra, C. R.* Investigation of molecular mechanisms and regulatory pathways of pro-angiogenic nanorods. Nanoscale 2015, 7, 9760-9770. ISI 2023 IF # 5.8.

Pal, A.; Ganguly, A.; Chowdhuri, S.; Yousuf, M.; Ghosh, A.; Barui, A. K.; Kotcherlakota, R.; Adhikari, S.*; Banerjee, R.* Bis-arylidene oxindole-betulinic acid conjugate: A fluorescent cancer cell detector with potent anticancer activity. ACS Medicinal Chemistry Letters 2015, 6, 612-616. ISI 2023 IF # 3.5.

Adela, R.; Nethi, S. K.; Bagul, P. K.; Barui, A. K.; Mattapally, S.; Kuncha, M; Patra, C. R.; Reddy, P. N. C.; Banerjee, S. K.* Hyperglycaemia enhances nitric oxide production in diabetes: A study from south Indian patients. Plos One 2015, 10(4), e0125270. ISI 2023 IF # 2.9.

Nagababu, P.$*; Barui, A. K.$ (Co-First Author); Thulasiram, B.$; Devi, C. S.; Satyanarayana, S.; Patra, C. R.*; Sreedhar, B.* Antiangiogenic activity of mononuclear copper(II) polypyridyl complexes for the treatment of cancers. Journal of Medicinal Chemistry 2015, 58, 5226-5241. ISI 2023 IF # 6.8. [$First three authors have equal contribution]

Nethi, S. K.; Mukherjee, S.; Veeriah, V.; Barui, A. K.; Chatterjee, S.; Patra, C. R.* Bioconjugated gold nanoparticles accelerate the growth of new blood vessels through redox signalling. Chemical Communications 2014, 50, 14367-14370. ISI 2023 IF # 4.3. [Highlighted in “Nature India” and “Hindustan Times”]

Wei, P-F.; Zhang, L.; Nethi. S. K.; Barui, A. K.; Lin, J.; Zhou, W.; Shen, Y.; Mana, N.; Zhang, Y-J.; Xu, J.; Patra, C. R.*; Wen, L-P.* Accelerating the clearance of mutant huntingtin protein aggregates through autophagy induction by europium hydroxide nanorods. Biomaterials 2014, 35(3), 899-907. ISI 2023 IF # 12.8.

Chereddy, N. R.*; Krishnan, S.; Barui, A. K.; Patra, C. R.*; Vaidya J. R.*; Thennarasu, S.* Donor atom selective coordination of Fe3+ and Cr3+ trigger fluorophore specific emission in a rhodamine–naphthalimide dyad. RSC Advances 2014, 4, 24324-24327. ISI 2023 IF # 3.9.

Patra, C. R.*; Barui, A. K. Nanoflowers: A future therapy for cardiac and ischemic disease? Nanomedicine 2013, 8(11), 1735-1738. ISI 2023 IF # 4.7.

Gayathri, T.$; Barui, A. K.$ (Co-First Author); Prashanthi, S.; Patra, C. R.*; Singh, S. P.* Meso-Substituted BODIPY fluorescent probes for cellular bio-imaging and anticancer activity. RSC Advances 2014, 4, 47409-47413. ISI 2023 IF # 3.9. [$First two authors have equal contribution]

Modak, A.$; Barui, A. K.$ (Co-First Author); Patra, C. R.*; Bhaumik, A.* A luminescent nanoporous hybrid material - based drug delivery system showing excellent theranostics potential for cancer. Chemical Communications 2013, 49, 7644-7646. ISI 2023 IF # 4.3. [Highlighted in “Nature India”] [$First two authors have equal contribution]

Mukherjee, S.; Sushma, V.; Patra, S.; Barui, A. K.; Bhadra, M. P.; Sreedhar, B.; Patra, C. R.* Green chemistry approach for the synthesis and stabilization of biocompatible gold nanoparticles and their potential applications in cancer therapy. Nanotechnology 2012, 23, 455103. ISI 2023 IF # 2.9. [Highlighted in “Nature India”, “The Hindu” and “Global Medical Discovery Alert”]

Patil, N. T.*; Shinde, V. S.; Thakare, M. S.; Kumar, P. H.; Bangal, P. R.; Barui, A. K.; Patra, C. R.* Exploiting the higher alkynophilicity of Au-species: Development of a highly selective fluorescent probe for gold ions. Chemical Communications 2012, 48, 11229-11231. ISI 2023 IF # 4.3.

Barui, A. K.; Veeriah, V.; Mukherjee, S.; Manna, J.; Patel, A. K.; Patra, S.; Pal, K.; Murali, S.; Rana, R. K.; Chatterjee, S.; Patra, C. R.* Zinc oxide nanoflowers make new blood vessels. Nanoscale 2012, 4(24), 7861-7869. ISI 2023 IF # 5.8. [Highlighted in “Nature India”, “The Hindu” and “Smart Brief”]

Awards and Honors / Achievements

Project

Junior Research Fellowship (Jan 2012 – Dec 2013) and Senior Research Fellowship (Jan 2014 – Dec 2016) from the University Grants Commission (UGC), Government of India by qualifying CSIR-UGC NET Examination to pursue Ph.D.

Project

Young Scientist Presentation Award in International Conference on Nanotechnology (ICNANO) “Lessons from Nature and Emerging Technologies” held on Jul 25 and 26, 2013 at Ansal University, Gurgaon, India.

Project

Best Poster Prize in 3rd International Conference on Advanced Nanomaterials and Nanotechnology (ICANN) held on Dec 01 to 03, 2013 at Indian Institute of Technology Guwahati (IIT Guwahati), Guwahati, India.

Project

Nanoscale Poster Prize (Royal Society of Chemistry) in 6th International Conference on Nano Science and Technology (ICONSAT) held on Mar 03 to 05, 2014 at Panjab University, Chandigarh, India.

Project

Editorial Board Member – BMC Cancer (Springer Nature; UK; IF#3.4)

Project

Topic Editor – MDPI, Switzerland [Pharmaceutics (IF#4.9), Cancers (IF#4.5), Nanomaterials (IF#4.4), Biomedicines (IF#3.9) & J. Clin. Med. (IF#3.0)]

Project

Early Career Reviewer Board – Biotechnology for Sustainable Materials (Springer Nature; UK)

Project

Invited Reviewer (Wiley): Advanced Science

Project

Invited Reviewer (Elsevier): Acta Biomaterialia; Materials Science and Engineering C; Colloids and Surfaces B: Biointerfaces;

Project

Invited Reviewer (American Chemical Society-ACS): ACS Applied Materials & Interfaces; ACS Applied Bio Materials

Project

Invited Reviewer (Royal Society of Chemistry-RSC): Journal of Materials Chemistry B; Nanoscale; Biomaterials Science; Food & Function; RSC Advances; New Journal of Chemistry;

Project

Invited Reviewer (Springer Nature): BMC Cancer; European Journal of Medical Research

Project

Invited Reviewer (Royal Society): Royal Society Open Science

Project

Invited Reviewer (Dove Medical Press): International Journal of Nanomedicine

Project

Member (MRSC) of the Royal Society of Chemistry (RSC), UK

Project

Member of the American Heart Association (AHA), USA

Project

Scientific Blogger-RSC Advances (Royal Society of Chemistry, UK; ISI 2023 IF # 3.9)

Project

Certificate of Achievement - Incelligent Expert (Cell Culture Quiz) – Merck Life Science, India